Product overview
Description Anti-DEFA1B rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human DEFA1B
Reactivity Human
Content 0.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol DEFA1B
Full name defensin, alpha 1B
Synonyms HP1; HP-1; HNP-1
Swissprot P59665
Target Background
Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense.
Anti-DEFA1B antibody Applications
Immunohistochemistry
Predicted cell location: cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 25-100 Predicted cell location: cytoplasm
Positive control: Human tonsil
Recommended dilution: 25-100