Anti-RARB antibody

Anti-RARB antibody

Cat. No. JC120010        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-RARB rabbit polyclonal antibody
Applications        ELISA, WB 
Immunogen               Fusion protein of human RARB
Reactivity                 Human, Mouse
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-RARB antibody
Target information
Symbol                 RARB
Full name                 retinoic acid receptor, beta
Synonyms    HAP; RRB2; NR1B2
Swissprot    P10826

Target Background
This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined.

Anti-RARB antibody
Applications
Western blotting
Predicted band size:50 kDa
Positive control:Human liver cancer and normal liver tissue 
Recommended dilution: 500-2000