Anti-CLDN3 antibody

Anti-CLDN3 antibody

Cat. No.   JC260401   
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-CLDN3 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human CLDN3
Reactivity                 Human
Content                     0.4 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 CLDN3
Full name                 claudin 3
Synonyms    RVP1, HRVP1, C7orf1, CPE-R2, CPETR3
Swissprot    O15551

Target Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.

Anti-CLDN3 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm, Cell membrane
Positive control: Human breast cancer
Recommended dilution: 25-100    Predicted cell location: Cytoplasm, Cell membrane
Positive control: Human colon cancer
Recommended dilution: 25-100