重组人原肌球蛋白α1链(TPM1)

特别提示：包括重组人原肌球蛋白α1链(TPM1)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人原肌球蛋白α1链(TPM1)
英文名称：Recombinant Human Tropomyosin alpha-1 Chain
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Met284在N端含有His标签。

TPM1质量控制：＞95%(还原性SDS-PAGE)

TPM1制剂：液体

TPM1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于TPM1：
Tropomyosin α-1 Chain (TPM1) is a member of the Tropomyosin family of highly conserved and widely distributed Actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM1 binds to Actin filaments in both muscle and non-muscle cells. It is one type of α-helical chain that forms the predominant Tropomyosin of striated muscle. TPM1 plays a central role in association with the Troponin complex and the Calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with Caldesmon. In non-muscle cells, it is implicated in stabilizing the cytoskeleton Actin filaments. Defects in TPM1 are associated with type 3 Familial Hypertrophic Cardiomyopathy.