Anti-USP15 antibody

Anti-USP15 antibody

Cat. No.     JC223515
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-USP15 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human USP15
Reactivity                 Human, Mouse, Rat
Content                     0.6 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 USP15
Full name                 ubiquitin specific peptidase 15
Synonyms    UNPH4; UNPH-2
Swissprot    Q9Y4E8

Target Background
This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human esophagus cancer
Recommended dilution: 25-100    Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 25-100