Anti-PAIP2 antibody

Anti-PAIP2 antibody

Cat. No.     JC164164
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-PAIP2 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human PAIP2
Reactivity                 Human, Mouse, Rat
Content                     0.6 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-PAIP2 antibody
Target information
Symbol                 PAIP2
Full name                 poly(A) binding protein interacting protein 2
Synonyms    PAIP-2; PAIP2A
Swissprot    Q9BPZ3

Target Background
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.

Anti-PAIP2 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human tonsil
Recommended dilution: 20-100    Predicted cell location: Cytoplasm
Positive control: Human esophagus cancer
Recommended dilution: 20-100