Anti-MSH2 antibody

Anti-MSH2 antibody

Cat. No.    JC163632  
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-MSH2 rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Synthetic peptide of human MSH2
Reactivity                 Human, Mouse
Content                     0.2 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-MSH2 antibody
Target information
Symbol                 MSH2
Full name                 mutS homolog 2
Synonyms    FCC1; COCA1; HNPCC; LCFS2; HNPCC1
Swissprot    P43246

Target Background
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Anti-MSH2 antibody
Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human lung cancer
Recommended dilution: 25-100    Predicted cell location: Nucleus
Positive control: Human ovarian cancer
Recommended dilution: 25-100