Product overview
Description Anti-CAPN1 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human CAPN1
Reactivity Human, Mouse, Rat
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CAPN1
Full name Calpain-1 catalytic subunit
Synonyms CANP, muCL, CANP1, CANPL1, muCANP
Swissprot P07384
Target Background
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.