Anti-MPP6 antibody

Anti-MPP6 antibody

Cat. No.     JC162472
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-MPP6 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human MPP6
Reactivity                 Human, Mouse
Content                     0.4 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-MPP6 antibody
Target information
Symbol                 MPP6
Full name                 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
Synonyms    VAM1; p55T; PALS2; VAM-1
Swissprot    Q9NZW5

Target Background
Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).

Anti-MPP6 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 30-150    Predicted cell location: Cytoplasm
Positive control: Human esophagus cancer
Recommended dilution: 30-150