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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海晶抗生物工程有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
1年
- 抗体英文名:
Anti-KLF2 antibody
- 宿主:
Rabbit
- 适应物种:
Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Sheep
- 应用范围:
科研试验
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Cat. No. JK163587
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-KLF2 rabbit polyclonal antibody
Applications ELISA, WB
Immunogen Synthetic peptide of human KLF2
Reactivity Human, Mouse, Rat
Content 0.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol KLF2
Full name Kruppel like factor 2
Synonyms LKLF
Swissprot Q9Y5W3
Target Background
The krüppel-type zinc finger transcription factors comprise a conserved family of DNA binding proteins that are important in developmental regulation. The krüppel zinc finger transcription factor was initially identified in Drosophila as a segmentation gene. Krüppel-like factors that have been characterized in mammals include erythroid krüppel-like transcription factor (EKLF), lung krüppel-like transcription factor (LKLF) and gut krüppel-like transcription factor (GKLF). EKLF is expressed principally in erythroid tissues, and LKLF expression is limited to the lung. GKLF is found predominantly in gut and has been shown to be expressed during growth arrest. In a developing mouse embryo, LKLF is necessary for normal tunica media formation and blood vessel stabilization. LKLF is also sufficient to program quiescence in T cells by negatively regulating the c-Myc-dependent pathway. The gene for human LKLF maps to chromosome 19p13.11.
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