Anti-NLRP10 antibody

Anti-NLRP10 antibody

Cat. No.    JC161961      
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-NLRP10 rabbit polyclonal antibody
Applications        ELISA, WB 
Immunogen               Synthetic peptide of human NLRP10
Reactivity                 Human, Mouse
Content                     1.1 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-NLRP10 antibody
Target information
Symbol                 NLRP10
Full name                 NLR family, pyrin domain containing 10
Synonyms    NOD8; PAN5; PYNOD; NALP10; CLR11.1
Swissprot    Q86W26

Target Background
Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.

Anti-NLRP10 antibody
Applications
Western blotting
Predicted band size:75 kDa
Positive control:Mouse heart and skeletal muscle tissue 
Recommended dilution: 500-2000