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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海机纯实业有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
12个月
- 抗体英文名:
Anti-F3 antibody
- 宿主:
Rabbit
- 适应物种:
人/动物/植物
- 应用范围:
ELISA, WB
- 浓度:
0.2 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Cat. No. JC221315
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-F3 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human F3
Reactivity Human
Content 0.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol F3
Full name Coagulation factor III (thromboplastin, tissue factor)
Synonyms TF; TFA; CD142
Swissprot P13726
Target Background
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.
Applications
Immunohistochemistry
Predicted cell location: Membrane, Cytoplasm
Positive control: Human ovarian cancer
Recommended dilution: 25-100 Predicted cell location: Membrane, Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 25-100
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