Product overview Description Anti-SOX2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human SOX2
Reactivity Human, Mouse
Content 0.1 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information Symbol SOX2
Full name SRY (sex determining region Y)-box 2
Synonyms ANOP3; MCOPS3
Swissprot P48431
Target Background This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
Applications Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 25-100 Predicted cell location: Cytoplasm
Positive control: Human ovarian cancer
Recommended dilution: 25-100