Anti-ALDH5A1 antibody

Anti-ALDH5A1 antibody

Cat. No.   JC261257
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-ALDH5A1 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human ALDH5A1
Reactivity                 Human, Mouse, Rat
Content                     0.4 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 ALDH5A1
Full name                 aldehyde dehydrogenase 5 family, member A1
Synonyms    SSDH; SSADH
Swissprot    P51649

Target Background
This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.

Anti-ALDH5A1 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 50-200    Predicted cell location: Cytoplasm
Positive control: Human colon cancer
Recommended dilution: 50-200