Anti-SIRT6 antibody

Anti-SIRT6 antibody

Cat. No.     JC221220
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-SIRT6 rabbit polyclonal antibody
Applications        ELISA, WB 
Immunogen               Fusion protein of human SIRT6
Reactivity                 Human, Mouse
Content                     0.2 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 SIRT6
Full name                 Sirtuin 6
Synonyms    SIR2L6
Swissprot    Q8N6T7

Target Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.

Applications
Western blotting
Predicted band size:39 kDa
Positive control:Mouse thymus tissue 
Recommended dilution: 500-2000