Anti-PIWIL4 antibody

Anti-PIWIL4 antibody

Cat. No.     JC221135
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-PIWIL4 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human PIWIL4
Reactivity                 Human, Mouse, Rat
Content                     0.2 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 PIWIL4
Full name                 piwi-like RNA-mediated gene silencing 4
Synonyms    HIWI2, MIWI2
Swissprot    Q7Z3Z4

Target Background
PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells.It plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity.May be involved in the chromatin-modifying pathway by inducing 'Lys-9' methylation of histone H3 at some loci.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm, Nucleus
Positive control: Human colon cancer
Recommended dilution: 50-200    Predicted cell location: Cytoplasm, Nucleus
Positive control: Human thyroid cancer
Recommended dilution: 50-200