Anti-KLRC1 antibody

Anti-KLRC1 antibody

Cat. No.     JC221037
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-KLRC1 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human KLRC1
Reactivity                 Human
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 KLRC1
Full name                 killer cell lectin-like receptor subfamily C, member 1
Synonyms    NKG2; NKG2A; CD159A
Swissprot    P26715

Target Background
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 50-200    Predicted cell location: Cytoplasm
Positive control: Human gastric cancer
Recommended dilution: 50-200