- 询价
- gelatins
- JC161612
- 进口/国产
- 2025年07月14日
- ELISA, WB
- Rabbit
- 人/动物/植物
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海机纯实业有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
12个月
- 抗体英文名：
Anti-DEAF1 antibody
- 宿主：
Rabbit
- 适应物种：
人/动物/植物
- 应用范围：
ELISA, WB
- 浓度：
0.5 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Cat. No. JC161612
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-DEAF1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human DEAF1
Reactivity Human
Content 0.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-DEAF1 antibody
Target information
Symbol DEAF1
Full name DEAF1 transcription factor
Synonyms SPN; NUDR; ZMYND5
Swissprot O75398
Target Background
Suppressin, also known as DEAF1 (deformed epidermal autoregulatory factor 1), SPN, NUDR (nuclear DEAF-1-related transcriptional regulator), or ZMYND5 (zinc finger MYND domain-containing protein 5), is a transcription factor required for embryonic development. Suppressin contains one SAND domain and one C-terminal MYND-type zinc finger. It interacts with LMO4 and CLIM-2, suggesting that it plays a role mediating cell fate and embryonic pattern formation. Suppressin is expressed in a variety of tissues and localizes to the nucleus. Several isoforms exist due to alternative splicing and, depending on the isoform, Suppressin is secreted in some cell types. Secreted Suppressin can function to inhibit cell proliferation, arresting cells in the G0 or G1 phase. Mutations in the gene encoding Suppressin may result in a growth advantage leading to the development and progression of neoplasia. This suggest that Supressin is a potential target for cancer therapy.
Anti-DEAF1 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human gasrtic cancer
Recommended dilution: 25-100 Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 25-100
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