Anti-IFT74 antibody

Anti-IFT74 antibody

Cat. No.    JC161571      
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-IFT74 rabbit polyclonal antibody
Applications        ELISA, WB 
Immunogen               Synthetic peptide of human IFT74
Reactivity                 Human
Content                     0.1 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-IFT74 antibody
Target information
Symbol                 IFT74
Full name                 intraflagellar transport 74 homolog (Chlamydomonas)
Synonyms    CMG1; CCDC2; CMG-1
Swissprot    Q96LB3

Target Background
Capillary morphogenesis protein 1 (CMG1), also known as intraflagellar transport protein 74 (ITP74) or coiled-coil domain-containing protein 2 (CCDC2), is a 600 amino acid human homologue of IFT-71, a complex B protein supporting intraflagellar transport (IFT) in Chlamydomonas. CMG1 localizes to the cytoplasmic vesicle and is highly expressed in adult and fetal kidney and testis, with lower levels of expression in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. CMG1 has been suggested to have a role in the primary cilia of HUVEC, and it also functions as a transcriptional regulator of cyclin D2 in spermatocyte-derived cells.

Anti-IFT74 antibody
Applications
Western blotting
Predicted band size:69 kDa
Positive control:HepG2 and 293T cells 
Recommended dilution: 500-2000