Anti-MCM7 antibody

Anti-MCM7 antibody

Cat. No.     JC220963
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-MCM7 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human MCM7
Reactivity                 Human
Content                     0.5 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 MCM7
Full name                 minichromosome maintenance complex component 7
Synonyms    MCM2; CDC47; P85MCM; P1CDC47; PNAS146; P1.1-MCM3
Swissprot    P33993

Target Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.

Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human thyroid cancer
Recommended dilution: 25-100    Predicted cell location: Nucleus
Positive control: Human cervical cancer
Recommended dilution: 25-100