Anti-XRCC6 antibody

Anti-XRCC6 antibody

Cat. No.     JC220909
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-XRCC6 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human XRCC6
Reactivity                 Human, Mouse
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 XRCC6
Full name                 X-ray repair complementing defective repair in Chinese hamster cells 6
Synonyms    ML8, KU70, TLAA, CTC75, CTCBF, G22P1
Swissprot    P12956

Target Background
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human esophagus cancer
Recommended dilution: 10-50    Predicted cell location: Nucleus
Positive control: Human colon cancer
Recommended dilution: 10-50