Product overview
Description Anti-EPHA5 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human EPHA5
Reactivity Human, Mouse, Rat
Content 0.7 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol EPHA5
Full name EPH receptor A5
Synonyms EK7; CEK7; EHK1; HEK7; EHK-1; TYRO4
Swissprot P54756
Target Background
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Alternatively spliced transcript variants encoding different isoforms have been described.