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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海机纯实业有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
12个月
- 抗体英文名:
Anti-SCN11A antibody
- 宿主:
Rabbit
- 适应物种:
人/动物/植物
- 应用范围:
ELISA, WB
- 浓度:
0.3 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Cat. No. JC161111
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-SCN11A rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human SCN11A
Reactivity Human, Mouse, Rat
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-SCN11A antibody
Target information
Symbol SCN11A
Full name sodium channel, voltage-gated, type XI, alpha subunit
Synonyms NaN; SNS-2; NAV1.9; SCN12A
Swissprot Q9UI33
Target Background
Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.
Anti-SCN11A antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm, Cell membrane
Positive control: Human esophagus cancer
Recommended dilution: 50-200 Predicted cell location: Cytoplasm, Cell membrane
Positive control: Human breast cancer
Recommended dilution: 50-200
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