Anti-PSPN antibody

Anti-PSPN antibody

Cat. No. JC160756        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-PSPN rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human PSPN
Reactivity                 Human
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-PSPN antibody
Target information
Symbol                 PSPN
Full name                 persephin
Synonyms    PSP
Swissprot    O60542

Target Background
The protein encoded by this gene is a neurotrophic factor, belonging to the GDNF family. Neurotrophic factors are important for the proper development and maintenance of the nervous system. These factors promote neuronal survival and can prevent the neuronal degeneration associated with injury, toxin exposure, or neurodegenerative disease. The encoded protein has amino acid similarity to its other family members, glial cell line-derived neurotrophic factor and neurturin. This gene product promotes the survival of ventral midbrain dopaminergic neurons in culture and prevents their degeneration after 6-hydroxydopamine treatment in vivo.

Anti-PSPN antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human colon cancer
Recommended dilution: 25-100    Predicted cell location: Cytoplasm
Positive control: Human ovarian cancer
Recommended dilution: 25-100