Anti-MUC5AC antibody

Anti-MUC5AC antibody

Cat. No.    JC160636        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-MUC5AC rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human MUC5AC
Reactivity                 Human
Content                     0.6 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-MUC5AC antibody
Target information
Symbol                 MUC5AC
Full name                 mucin 5AC, oligomeric mucus/gel-forming
Synonyms    TBM, leB, MUC5
Swissprot    P98088

Target Background
Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease (COPD). Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system. Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum.

Anti-MUC5AC antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human breast cancer
Recommended dilution: 50-200