Product overview
Description Anti-MAP1LC3C rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human MAP1LC3C
Reactivity Human
Content 0.8 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol MAP1LC3C
Full name microtubule-associated protein 1 light chain 3 gamma
Synonyms LC3C; ATG8J
Swissprot Q9BXW4
Target Background
Autophagy is a highly regulated bulk degradation process that plays an important role in cellular maintenance and development. MAP1LC3C is an ortholog of the yeast autophagosome protein Atg8. Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruites all ATG8 family members to infecting bacteria such as S.Typhimurium.