Anti-JAK1 antibody

Anti-JAK1 antibody

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  • 询价
  • gelatins
  • JC263046
  • 上海
  • 2025年07月12日
  • Rabbit
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    • 详细信息
    • 技术资料
    • 供应商

      江西江蓝纯生物试剂有限公司

    • 库存

      大量

    • 克隆性

      多克隆

    • 保质期

      1年

    • 抗体英文名

      Anti-JAK1 antibody

    • 宿主

      Rabbit

    • 浓度

      0.6 mg/ml

    • 保存条件

      -20°C

    • 规格

      25 μl/100 μl/200 μl

    Anti-JAK1 antibody

    Cat. No.     JC263046
    Package    25 μl/100 μl/200 μl
    Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

    Product overview
    Description                   Anti-JAK1 rabbit polyclonal antibody
    Applications        ELISA, IHC 
    Immunogen               Synthetic peptide of human JAK1
    Reactivity                 Human, Mouse
    Content                     0.6 mg/ml
    Host species               Rabbit
    Ig class                  Immunogen-specific rabbit IgG
    Purification                 Antigen affinity purification

    Target information
    Symbol                 JAK1
    Full name                 Janus kinase 1
    Synonyms    JTK3; JAK1A; JAK1B
    Swissprot    P23458

    Target Background
    Janus kinase 1 (JAK1), is a member of a new class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The second phosphotransferase domain bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein. JAK1 is involved in the interferon-alpha/beta and -gamma signal transduction pathways. The reciprocal interdependence between JAK1 and TYK2 activities in the interferon-alpha pathway, and between JAK1 and JAK2 in the interferon-gamma pathway, may reflect a requirement for these kinases in the correct assembly of interferon receptor complexes. These kinases couple cytokine ligand binding to tyrosine phosphorylation of various known signaling proteins and of a unique family of transcription factors termed the signal transducers and activators of transcription, or STATs.
    Anti-JAK1 antibody
    Applications
    Immunohistochemistry
    Predicted cell location: Cytoplasm
    Positive control: Human tonsil
    Recommended dilution: 25-100    
                
    The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using ml263046(JAK1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)    

    ELISA
    Recommended dilution: 500-1000

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    资料下载:

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