Anti-DES antibody

Anti-DES antibody

Cat. No.     JC262991
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-DES rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Synthetic peptide of human DES
Reactivity                 Human, Mouse, Rat
Content                     0.7 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 DES
Full name                 desmin
Synonyms    CSM1; CSM2; LGMD2R
Swissprot    P17661

Target Background
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human breast cancer
Recommended dilution: 25-100    
            
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using ml262991(DES Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)    
Western blotting
Predicted band size:54 kDa
Positive control:Jurkat and Hela cell 
Recommended dilution: 200-1000