Anti-SEPW1 antibody

Anti-SEPW1 antibody

Cat. No.     JC262953
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-SEPW1 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human SEPW1
Reactivity                 Human, Mouse, Rat
Content                     0.7 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 SEPW1
Full name                 selenoprotein W, 1
Synonyms    selW
Swissprot    P63302

Target Background
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein shows highest expression in skeletal muscle and heart, and may be involved in oxidation-reduction reactions. A retroprocessed pseudogene, SEPW1P, has been identified and mapped to chromosome 1p35-34.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human colorectal cancer
Recommended dilution: 25-100    
            
The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using ml262953(SEPW1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)    

ELISA
Recommended dilution: 5000-10000