- 询价
- gelatins
- JC125090
- 进口/国产
- 2025年07月11日
- ELISA, WB
- Rabbit
- 人/动物/植物
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海机纯实业有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
12个月
- 抗体英文名：
Anti-IGHA1 antibody
- 宿主：
Rabbit
- 适应物种：
人/动物/植物
- 应用范围：
ELISA, WB
- 浓度：
0.9 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Anti-IGHA1 antibody
Cat. No. JC125090
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-IGHA1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human IGHA1
Reactivity Human
Content 0.9 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-IGHA1 antibody
Target information
Symbol IGHA1
Full name immunoglobulin heavy constant alpha 1
Synonyms IgA1
Swissprot P01876
Target Background
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). Ig alpha is the major immunoglobulin class in body secretions (PubMed:2241915).
Anti-IGHA1 antibody
Applications
Immunohistochemistry
Predicted cell location: Secreted, Cell membrane
Positive control: Human cervical cancer
Recommended dilution: 50-300 Predicted cell location: Secreted, Cell membrane
Positive control: Human colorectal cancer
Recommended dilution: 50-300
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