Anti-PDPN antibody

Anti-PDPN antibody

Cat. No.     JC262603
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-PDPN rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Synthetic peptide of human PDPN
Reactivity                 Human
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 PDPN
Full name                 podoplanin
Synonyms    T1A; GP36; GP40; Gp38; OTS8; T1A2; TI1A; T1A-2; AGGRUS; HT1A-1; PA2.26
Swissprot    Q86YL7

Target Background
This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.

Applications
Immunohistochemistry
Predicted cell location: Cell membrane
Positive control: Human liver cancer
Recommended dilution: 10-50    
            
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml262603(PDPN Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)    
Western blotting
Predicted band size:17 kDa; 25 kDa
Positive control:Human fetal brain tissue, Hela and 293T cells 
Recommended dilution: 200-1000