Anti-CD70 antibody

Anti-CD70 antibody

Cat. No.     JC262502
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-CD70 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human CD70
Reactivity                 Human
Content                     0.7 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 CD70
Full name                 CD70 molecule
Synonyms    CD27L; CD27LG; TNFSF7
Swissprot    P32970

Target Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

Applications
Immunohistochemistry
Predicted cell location: Cell membrane
Positive control: Human liver cancer
Recommended dilution: 30-150    Predicted cell location: Cell membrane
Positive control: Human breast cancer
Recommended dilution: 30-150
            
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml262502(CD70  Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)    The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using ml262502(CD70  Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)

ELISA
Recommended dilution: 2000-10000