Anti-COPS6 antibody

Anti-COPS6 antibody

Cat. No.     JC124629        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-COPS6 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Full length fusion protein
Reactivity                 Human, Mouse
Content                     0.6 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-COPS6 antibody
Target information
Symbol                 COPS6
Full name                 COP9 signalosome subunit 6
Synonyms    CSN6; MOV34-34KD
Swissprot    Q7L5N1

Target Background
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.

Anti-COPS6 antibody
Applications
Immunohistochemistry
Predicted cell location: Nucleus or Cytoplasm
Positive control: Human esophagus cancer
Recommended dilution: 20-100    Predicted cell location: Nucleus or Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 20-100