- 询价
- Signalway Antibody
- USA
- AP79359
- 2025年07月13日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Microtubule-associated proteins 1A/1B light chain 3B
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:E.coli
purification:Greater than 95% by SDS-PAGE
specificity:Human
other_names:MAP1ALC3,Autophagy-related protein LC3 B,Autophagy-related ubiquitin-like modifier LC3 B,MAP1 light chain 3-like protein 2,MAP1A/MAP1B light chain 3 B,Microtubule-associated protein 1 light chain 3 beta,MAP1A/MAP1B LC3 B
accession_no:Q9GZQ8
Gene name:MAP1LC3B
calculated_mw:13.75
tag info:His
Immunogen Description:1-125AA
formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
storage:Store at -20C. (Avoid repeated freezing and thawing.)
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
产品详细信息请点击：Microtubule-associated proteins 1A/1B light chain 3B
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文献和实验微管结合蛋白(microtubule-associated proteins, MAPs)
与微管特异地结合在一起, 对微管的功能起辅助作用的蛋白质称为微管结合蛋白, 在微管结构中约占10～15%。 一类主要的MAPs家族叫作装配MAPs(assembly MAPs), 作用是将微管在胞质溶胶中进行交联。这些MAPs的结构中具有两个结构域, 一个是碱性的微管蛋白结合结构域, 另一个是酸性的外伸的结构域。 根据序列特点, 将MAPs分成两个主要的类型:Ⅰ型和Ⅱ型(还有其他类型)。MAP1A和MAP1B含有几个重复的氨基酸序列:Lys-Lys-Glu
Structure and Properties of Human Immunoglobulin Light-Chain Dimers
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