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- 详细信息
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Phylloquinone omega-hydroxylase CYP4F2
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:E.coli
purification:>90% by SDS-PAGE
specificity:Human
other_names:1.14.13.-,1.14.13.30,20-hydroxyeicosatetraenoic acid synthase,Arachidonic acid omega-hydroxylase,CYPIVF2,Cytochrome P450 4F2,Cytochrome P450-LTB-omega,Leukotriene-B(4) 20-monooxygenase 1,Leukotriene-B(4) omega-hydroxylase 1,20-HETE synthase
accession_no:P78329
Gene name:CYP4F2
calculated_mw:
tag info:His
Immunogen Description:Recombinant protein
formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
storage:Store at -20C. (Avoid repeated freezing and thawing.)
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:19297519, PubMed:24138531). Also shows arachidonic acid omega-hydroxylase activity in kidney, by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), possibly influencing blood pressure control (PubMed:10660572, PubMed:17341693, PubMed:18574070). Also acts as a leukotriene-B(4) omega-hydroxylase by mediating conversion of leukotriene-B(4) (LTB4) to its omega-hydroxylated metabolite 20-hydroxyleukotriene-B(4) (20-OH LTB4) (PubMed:8026587, PubMed:9799565).
产品详细信息请点击：Phylloquinone omega-hydroxylase CYP4F2
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