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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20˚C
- 英文名:
Dual specificity protein phosphatase 1
- 库存:
详询
- 供应商:
南京莱富赛
- 规格:
详询
host_species:E.coli
purification:Greater than 95% by SDS-PAGE
specificity:Human
other_names:CL100,MKP1,PTPN10,VH1,Dual specificity protein phosphatase hVH1,Mitogen-activated protein kinase phosphatase 1,Protein-tyrosine phosphatase CL100,MAP kinase phosphatase 1
accession_no:P28562
Gene name:DUSP1
calculated_mw:6.93
tag info:His
Immunogen Description:305-367AA
formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
storage:Store at -20C. (Avoid repeated freezing and thawing.)
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
产品详细信息请点击:Dual specificity protein phosphatase 1
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文献和实验Functional Studies of Dual-Specificity Phosphatases
Dual-speclflcity phosphatases, a subfamily enzymes of protein tyrosine phosphatases, play important roles in signal transduction and cell-cycle regulation during cell growth and differentiation (1 ). Unlike classic tyrosme phosphatases
CDC25 Dual-Specificity Protein Phosphatases: Detection and Activity Measurements
Most cyclin-dependent kinases are negatively regulated by phosphorylation of two residues, a threonine at residue 14 and a tyrosine at residue 15. These residues are dephosphorylated by the cdc25 family of dual-specificity phosphatases
Discovery of Protein Kinase Phosphatase Inhibitors
with chemical biology and high-content multiparametric analyses and was developed as a screening approach to discover protein phosphatase inhibitors. Using a dual specificity mitogen-activated protein kinase phosphatase as an example, a detailed protocol
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