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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件:
Store at -20˚C
- 英文名:
3-hydroxy-3-methylglutaryl-coenzyme A reductase
- 库存:
详询
- 供应商:
南京莱富赛
- 规格:
详询
host_species:E.coli
purification:>90% by SDS-PAGE
specificity:Human
other_names:null
accession_no:P04035
Gene name:HMGCR
calculated_mw:
tag info:His
Immunogen Description:Recombinant protein
formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
storage:Store at -20C. (Avoid repeated freezing and thawing.)
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.
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- 作者
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- 询问日期
文献和实验Lysosomal Acid Lipase: Assay and Purification
of intracellular lipid metabolism by three mechanisms: (1) free cholesterol reduces the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA)-reductase, the key enzyme of cholesterol synthesis (4 ) (2) cholesterol activates its own esterification by acyl-CoA
Isolation of Parasite Genes Using Synthetic Oligonucleotides
subunit genes of Trypanosoma brucei (8 ) and of P. falciparum (9 ), and the 3-hydroxy-3-methylglutaryl-coenzyme A reduc tase from Schistosoma mansoni (10 ). It has been of particular utility in the case of P. falciparum (11 ), whose extremely A + T
Metabolic Labeling of Prenyl and Carboxyl‐Methyl Groups
, M.S., and Goldstein, J.L. 1980. Feedback regulation of 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase in livers of mice treated with mevinolin, a competitive inhibitor of the reductase. J. Clin. Invest. 66:1094‐1107
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