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Ectonucleotide pyrophosphatase

/phosphodiesterase family member 1
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  • Signalway Antibody已认证
  • USA
  • AP78758
  • 2025年07月15日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      Store at -20˚C

    • 英文名

      Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

    • 库存

      详询

    • 供应商

      南京莱富赛

    • 规格

      详询

    host_species:E.coli

    purification:>90% by SDS-PAGE

    specificity:Rat

    other_names:Npps,Pc1,Pdnp1,Phosphodiesterase I/nucleotide pyrophosphatase 1,Plasma-cell membrane glycoprotein PC-1

    accession_no:Q924C3
    Gene name:Enpp1

    calculated_mw:

    tag info:His

    Immunogen Description:Recombinant protein

    formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)

    storage:Store at -20C. (Avoid repeated freezing and thawing.)
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

    background:By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity.

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    Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
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