- 询价
- Signalway Antibody
- USA
- AP78557
- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Metalloproteinase inhibitor 1
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:E.coli
purification:Greater than 90% by SDS-PAGE
specificity:Mouse
other_names:Timp,Timp-1,Collagenase inhibitor 16C8 fibroblast,Erythroid-potentiating activity,TPA-S1,TPA-induced protein,Tissue inhibitor of metalloproteinases 1,EPA,TIMP-1
accession_no:P12032
Gene name:Timp1
calculated_mw:19.91
tag info:His
Immunogen Description:25-205aa
formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
storage:Store at -20C. (Avoid repeated freezing and thawing.)
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14 (By similarity). Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling.
产品详细信息请点击：Metalloproteinase inhibitor 1
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文献和实验(Table 1 ). The enzymatic activity of MMP family members is controlled by a group of inhibitor proteins known as the Tissue Inhibitors of Metalloproteinases (TIMPs), which consist of four family members (Table 2 ). Whereas all four TIMPs can inhibit
Regulation of Angiostatin Mobilization by Tumor-Derived Matrix Metalloproteinase-2
. Our interest in this area stemmed from our discovery of angiostatin (1) , a 38 kDa internal fragment of plasminogen that is a specific inhibitor of capillary endothelial cell proliferation in vitro and angiogenesis in vivo. By inhibiting angiogenesis, angiostatin
Cardiac Stem Cell Niche, MMP9, and Culture and Differentiation of Embryonic Stem Cells
. Here, we describe the method of ESC culture and differentiation, and the expression of MMP9 and its inhibitor, tissue inhibitor of metalloproteinase-4 (TIMP4) in differentiating ESC.
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