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- Signalway Antibody
- USA
- AP78410
- 2025年07月11日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Vascular endothelial growth factor A
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:E.coli
purification:Greater than 95% by SDS-PAGE
specificity:Human
other_names:VEGF,Vascular permeability factor,VPF
accession_no:P15692
Gene name:VEGFA
calculated_mw:22.66
tag info:His
Immunogen Description:27-232aa
formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
storage:Store at -20C. (Avoid repeated freezing and thawing.)
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development.
产品详细信息请点击：Vascular endothelial growth factor A
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文献和实验to establish that antibodies targeting the epidermal growth factor receptor and vascular endothelial growth factor receptor-2 are synergistic with regard to antitumor effects, in a BxPC-3 subcutaneous xenograft model for pancreatic cancer.
Vascular Endothelial Growth Factor Expression in Non-Small Cell Lung Cancer
Lung cancer is the most common cause of cancer-related death in the western world. Of patients with lung cancer, in the region of 90% are either current or ex-cigarette smokers. Non-small cell lung cancer (NSCLC) accounts for approx 80
PriCells: Primary cells culture with supplement of vascular endothelial growth factor (VEGF)
PriCells: Primary cells culture with supplement of vascular endothelial growth factor (VEGF) Introduction Vascular endothelial growth factor (VEGF) is a signal protein produced by cells that inspires the growth of new blood vessels.
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