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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20˚C
- 英文名:
Connective tissue growth factor
- 库存:
详询
- 供应商:
南京莱富赛
- 规格:
详询
host_species:E.coli
purification:>90% by SDS-PAGE
specificity:Human
other_names:CCN2,HCS24,IGFBP8,CCN family member 2,Hypertrophic chondrocyte-specific protein 24,Insulin-like growth factor-binding protein 8,IBP-8
accession_no:P29279
Gene name:CTGF
calculated_mw:
tag info:His
Immunogen Description:CAYRLEDTFGPDPTMI
formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
storage:Store at -20C. (Avoid repeated freezing and thawing.)
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
产品详细信息请点击:Connective tissue growth factor
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文献和实验the formation of scar tissue throughout the body. Furthermore, connective tissue growth factor (CTGF) has been shown to mediate most of the fibrotic actions of TGF-β, including stimulation of synthesis of extracellular matrix and differentiation of fibroblasts
胶样组织 mucous connective tissue.gelatinous connective tissue
保有间充质特征而尚未分化的纤维性结缔组织,在高等动物的胚胎皮肤下面可以看到。构成哺乳类脐带主要组织的渥顿氏软肉,就是这种组织的代表。细胞体是大形的星状细胞或者是梭状细胞,其细胞浆的突起,经常和邻近的细胞突起愈合。其中也有少数巨噬细胞和游离淋巴细胞。充填在细胞间的基质,为均质的胶胨样物质,但在固定之后则出现颗粒状以及纤维状的沉淀。另外含有微量的细胶原纤维。随着胚的发育,胶原纤维增加。胶胨样的基质和其它结缔组织的基质相同,软骨素硫酸和糖醛酸是主要的构成成分。
Assaying Growth Factor Activity of Tissue Inhibitors of Metalloproteinases
three methods for assaying the growth factor activity of TIMPs, that is, the direct counting of cell number, the measurement of DNA content for cell proliferation, and the [3 H]thymidine incorporation assay for cell mitogen activity.
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