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- 文献和实验
- 技术资料
- 保存条件:
Store at -20˚C
- 英文名:
Recombinant Rat Integrin beta-4(Itgb4),partial
- 库存:
详询
- 供应商:
南京莱富赛
- 规格:
详询
host_species:in vitro E.coli expression system
purification:Greater than 85% as determined by SDS-PAGE.
other_names:GP150 CD_antigen: CD104
accession_no:Q64632
calculated_mw:92.2 kDa
tag info:N-terminal 6xHis-SUMO-tagged
Immunogen Description:Expression Region:28-713aa
Sequence Info:Extracellular Domain
formulation:Tris-based buffer50% glycerol
storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Integrin alpha-6,beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling
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Introduction of human 14-3-3 proteins
with a 29-kDa protein with partial sequences identical to 14-3-3zeta.In this study,the interaction between GPIb-IX and recombinant 14-3-3zeta is reconstituted.Further,we show that the 14-3-3zeta binding site in GPIb is within a 15 residue sequence at the C
Genetic and Pharmacologic Models for Type 1 Diabetes
by a partial or total insufficiency of insulin. The premiere animal model of autoimmune T cell?mediated T1D is the NOD mouse. A dominant negative mutation in the mouse insulin 2 gene ( Ins2 Akita ) produces a severe insulin deficiency syndrome
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