- 询价
- Signalway Antibody
- USA
- AP78043
- 2026年03月08日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Recombinant Rabbit Tropomyosin alpha-1 chain(TPM1)
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:Baculovirus
purification:Greater than 85% as determined by SDS-PAGE.
other_names:Alpha-tropomyosin Tropomyosin-1 TPMA
accession_no:P58772
calculated_mw:36.7 kDa
tag info:N-terminal 10xHis-tagged and C-terminal Myc-tagged
Immunogen Description:Expression Region:1-284aa
Sequence Info:Full Length
formulation:Tris-based buffer50% glycerol
storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
产品详细信息请点击：Recombinant Rabbit Tropomyosin alpha-1 chain(TPM1)
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文献和实验Protein purification: tropomyosin
Overview TROPOMYOSIN An ubiquitous actin binding protein arranged in alpha-helical coiled-coil of 410 Angstrom length
Selection of Recombinant Antibodies by Eukaryotic Ribosome Display
Ribosome display is a powerful method for selection of single-chain antibodies in vitro. It operates through the formation of libraries of antibody–ribosome–mRNA complexes that are selected on immobilized antigen, followed by recovery
ITGA4（CD49D）信号通路、病理作用与靶向治疗药物研究梳理
整合素alpha 4（ITGA4），又称CD49D，是整合素家族的关键亚基。它通过与β1或β7亚基结合，形成功能性异二聚体α4β1（VLA-4）和α4β7，在免疫细胞的黏附、运输及迁移中扮演核心角色。VLA-4还能介导白细胞在活化内皮细胞上的聚集。鉴于ITGA4在多发性硬化、炎症性肠病等多种自身免疫性疾病的病理过程中发挥关键作用，它已成为治疗干预的重要靶点。 ITGA4的表达分布 ITGA4主要分布于巨核细胞、红细胞、干细胞、NK细胞以及T细胞中。在T细胞亚群中，CD49D主要在CD
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