- 询价
- Signalway Antibody
- USA
- AP77833
- 2026年03月05日
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- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Recombinant Conus vexillum Alpha-conotoxin VxXXC
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:E.coli
purification:Greater than 85% as determined by SDS-PAGE.
other_names:VxXIIC
accession_no:P0C1W7
calculated_mw:25.3 kDa
tag info:N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged
Immunogen Description:Expression Region:1-47aa
Sequence Info:Full Length
formulation:Tris-based buffer50% glycerol
storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin specifically blocks mammalian neuronal nAChR of the alpha-7,CHRNA7, alpha-3-beta-2,CHRNA3-CHRNB2 and alpha-4-beta-2,CHRNA4-CHRNB2 subtypes. VxXXA and VxXXB inhibit alpha-7,CHRNA7 and alpha-3-beta-2,CHRNA3-CHRNB2 nAChR more efficiently than VxXXC. VxXXB is the most effective at inhibiting alpha-4-beta-2,CHRNA4-CHRNB2 nAChR, followed by VxXXC and VxXXA.
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