Recombinant Conus vexillum Alp

host_species:E.coli

purification:Greater than 85% as determined by SDS-PAGE.

other_names:VxXIIC

accession_no:P0C1W7

calculated_mw:25.3 kDa

tag info:N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged

Immunogen Description:Expression Region:1-47aa
Sequence Info:Full Length

formulation:Tris-based buffer50% glycerol

storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

background:Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin specifically blocks mammalian neuronal nAChR of the alpha-7,CHRNA7, alpha-3-beta-2,CHRNA3-CHRNB2 and alpha-4-beta-2,CHRNA4-CHRNB2 subtypes. VxXXA and VxXXB inhibit alpha-7,CHRNA7 and alpha-3-beta-2,CHRNA3-CHRNB2 nAChR more efficiently than VxXXC. VxXXB is the most effective at inhibiting alpha-4-beta-2,CHRNA4-CHRNB2 nAChR, followed by VxXXC and VxXXA.

产品详细信息请点击：Recombinant Conus vexillum Alpha-conotoxin VxXXC