Recombinant Epstein-Barr virus

host_species:E.coli

purification:Greater than 85% as determined by SDS-PAGE.

other_names:

accession_no:P03211

calculated_mw:35.8 kDa

tag info:N-terminal 6xHis-SUMO-tagged

Immunogen Description:Expression Region:458-641aa
Sequence Info:Partial

formulation:Tris-based buffer50% glycerol

storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

background:Plays an essential role in replication and partitioning of viral genomic DNA during latent viral infection. During this phase, the circular double-stranded viral DNA undergoes replication once per cell cycle and is efficiently partitioned to the daughter cells. EBNA1 activates the initiation of viral DNA replication through binding to specific sites in the viral latent origin of replication, oriP. Additionally, it governs the segregation of viral episomes by mediating their attachment to host cell metaphase chromosomes. Also activates the transcription of several viral latency genes. Finally, it can counteract the stabilization of host p53,TP53 by host USP7, thereby decreasing apoptosis and increasing host cell survival.

产品详细信息请点击：Recombinant Epstein-Barr virus Epstein-Barr nuclear antigen 1(EBNA1),partial