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- Signalway Antibody
- USA
- AP77724
- 2025年07月13日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Recombinant Epstein-Barr virus Epstein-Barr nuclear antigen 1(EBNA1),partial
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:E.coli
purification:Greater than 85% as determined by SDS-PAGE.
other_names:
accession_no:P03211
calculated_mw:35.8 kDa
tag info:N-terminal 6xHis-SUMO-tagged
Immunogen Description:Expression Region:458-641aa
Sequence Info:Partial
formulation:Tris-based buffer50% glycerol
storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Plays an essential role in replication and partitioning of viral genomic DNA during latent viral infection. During this phase, the circular double-stranded viral DNA undergoes replication once per cell cycle and is efficiently partitioned to the daughter cells. EBNA1 activates the initiation of viral DNA replication through binding to specific sites in the viral latent origin of replication, oriP. Additionally, it governs the segregation of viral episomes by mediating their attachment to host cell metaphase chromosomes. Also activates the transcription of several viral latency genes. Finally, it can counteract the stabilization of host p53,TP53 by host USP7, thereby decreasing apoptosis and increasing host cell survival.
产品详细信息请点击：Recombinant Epstein-Barr virus Epstein-Barr nuclear antigen 1(EBNA1),partial
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文献和实验Genetic Analysis and Gene Expression with Mini-Epstein-Barr Virus Plasmids
Upon infection with Epstein-Barr virus (EBV), primary human B-lymphocytes are efficiently immortalized and give rise to lymphoblastoid cell lines in vitro. Four of the 11 viral genes expressed in the immortalized B cells
Determination of Antigen and Fine Peptide Specificity of EBV-Specific CTLs
Currently, the antigen specificity of Epstein-Barr virus (EBV)-specific cytotoxic T cells (CTLs) can be determined using a set of recombinant vaccinia viruses expressing individual EBV proteins. These recombinant viruses are used to infect
Malignant Transformation and Immortalization Assays in Animal Cells Transfected with the BARF1 Gene
Epstein-Barr virus (EBV) is associated with both lymphoma (for example, Burkitt’s lymphoma) and epithelial carcinoma (for example, nasopharyngeal carcinoma). Among about 90 genes encoded by the virus (1 ), seven latent genes—(Epstein-Barr
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