- 询价
- Signalway Antibody
- USA
- AP77649
- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Recombinant Mouse 14-3-3 protein beta,alpha(Ywhab)
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:Yeast
purification:Greater than 85% as determined by SDS-PAGE.
other_names:Protein kinase C inhibitor protein 1
accession_no:Q9CQV8
calculated_mw:30.6 kDa
tag info:N-terminal 10xHis-tagged
Immunogen Description:Expression Region:1-246aa
Sequence Info:Full Length
formulation:Tris-based buffer50% glycerol
storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13.
产品详细信息请点击：Recombinant Mouse 14-3-3 protein beta,alpha(Ywhab)
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文献和实验hydroxylaseAssociation of a 14-3-3 protein with CMP-NeuAc:GM1 alpha 2,3-sialyltransferaseInteraction of 14-3-3 with signaling proteins is mediated by phosphoserineActivation-modulated association of 14-3-3 proteins with Cbl14-3-3 binding sequence in cytoplasmic domain
Introduction of human 14-3-3 proteins
-----------------------Site of interaction of 14-3-3 protein with phosphorylated tryptophan hydroxylaseAssociation of a 14-3-3 protein with CMP-NeuAc:GM1 alpha 2,3-sialyltransferaseInteraction of 14-3-3 with signaling proteins is mediated by phosphoserineActivation-modulated
(9 ). Because its systemic administration was shown to mediate the regression of some mouse tumors (10 ), TNF-α has attracted much attention as a potential antitumor reagent (11 ). However, the problem of its dose-dependent toxicity has been particularly apparent in human
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