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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20˚C
- 英文名:
Recombinant Mouse Peroxisome proliferator-activated receptor gamma(Pparg)
- 库存:
详询
- 供应商:
南京莱富赛
- 规格:
详询
host_species:E.coli
purification:Greater than 85% as determined by SDS-PAGE.
other_names:Nuclear receptor subfamily 1 group C member 3
accession_no:P37238
calculated_mw:73.6 kDa
tag info:N-terminal 6xHis-SUMO-tagged
Immunogen Description:Expression Region:1-505aa
Sequence Info:Full Length of Isoform 2
formulation:Tris-based buffer50% glycerol
storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL,BMAL1 in the blood vessels
产品详细信息请点击:Recombinant Mouse Peroxisome proliferator-activated receptor gamma(Pparg)
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文献和实验Adipose Tissue-Specific PPAR Gene Targeting
The nuclear receptor peroxisome proliferator activated receptor gamma (PPARγ) is most abundantly expressed in adipose tissue and has been shown to play imperative roles in controlling adipogenesis and lipogenesis in cultured
Peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α) is a nuclear transcriptional coactivator that regulates the genes involved in energy metabolism. Recent evidence has been provided that alternative splicing
Performing Bronchoalveolar Lavage in the Mouse
response by the peroxisome proliferator‐activated receptor‐alpha agonist fenofibrate. Eur. J. Pharmacol. 581:177‐184. Deschamps, K., Cromlish, W., Weicker, S., Lamontagne, S
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