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- Signalway Antibody
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- AP76548
- 2025年07月09日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Recombinant Human Transcriptional enhancer factor TEF-3(TEAD4),partial
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:E.coli
purification:Greater than 90% as determined by SDS-PAGE.
other_names:TEA domain family member 4 ;TEAD-4Transcription factor 13-like 1Transcription factor RTEF-1
accession_no:Q15561
calculated_mw:56.7 kDa
tag info:N-terminal 6xHis-SUMO-tagged
Immunogen Description:Expression Region:74-434aa
Sequence Info:Partial
formulation:Tris-based buffer50% glycerol
storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1,MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1,2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1,TAZ. Acts by mediating gene expression of YAP1 and WWTR1,TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (T) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif.
产品详细信息请点击：Recombinant Human Transcriptional enhancer factor TEF-3(TEAD4),partial
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