Recombinant Human Toll-like re

host_species:E.coli

purification:Greater than 90% as determined by SDS-PAGE.

other_names:Toll,interleukin-1 receptor-like protein 4; CD282

accession_no:O60603

calculated_mw:80.4 kDa

tag info:N-terminal 6xHis-SUMO-tagged

Immunogen Description:Expression Region:19-588aa
Sequence Info:Extracellular Domain

formulation:Tris-based buffer50% glycerol

storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

background:Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

产品详细信息请点击：Recombinant Human Toll-like receptor 2(TLR2),partial