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- Signalway Antibody
- USA
- AP76232
- 2026年02月13日
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- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Recombinant Mouse α-Synuclein,SNCA
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:E.coli
purification:Greater than 95% as determined by reducing SDS-PAGE.
specificity:Mouse
accession_no:O55042
calculated_mw:14.5kDa
formulation:Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
reconstitution:Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg,ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
storage:Lyophilized protein should be stored at < -20C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20C for 3 months.
产品详细信息请点击：Recombinant Mouse α-Synuclein,SNCA
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文献和实验α-Synuclein/Amyloid Interactions
with senile plaques in brain sections and with Aβ peptides in solution. Information on the following points are found in Jensen et al. (5 ) and references therein: (1 ) Expression and purification of recombinant human α-synuclein; (2 ) methodology
with a Ca2+ -free medium or with trypsin/dispase. The latter facilitates the introduction of recombinant or trappable probes and microimaging studies of, for example, changes in cytosolic-free Ca2+ concentration or the dynamics of individual organelles
）、静止性震颤（手、腿或下颌在放松时不自主抖动）、肌张力增高（肢体僵硬、活动阻力增加）以及姿势不稳（易跌倒、平衡能力下降）。此外，患者常伴有非运动症状，如嗅觉减退、睡眠障碍、便秘、抑郁和认知功能下降等，这些表现可早于运动症状出现，严重影响生活质量。 帕金森病发病机制 帕金森病（PD）的核心病理特征是中脑黑质致密部多巴胺能神经元的进行性丢失，以及细胞内以α-突触核蛋白（α-synuclein, α-syn）为主要成分的路易小体形成。研究表明，α-syn的异常聚集与错误折叠是疾病启动和进展
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